Product Description
| Specifications: | |
| Packaging | 50 tablets (1 x 50) |
| Concentration | 20 mg/tablet |
| Active Substance | Isotretinoin |
| Active Half-life | 10-20 hours |
| Group | Skin Care |
| Subgroup | Retinoid |
| Recommended Dosage | Dose: 0.5-1mg/kg body weight per day. Course typically 16-24 weeks. |
| Oil-based / Base | N/A (Oral tablet) |
| Retains Water | N/A |
| Aromatization | N/A |
| Product Description: | |
| What It Is and How It Works | |
| Isotretinoin, sold under brand names including Accutane and Roaccutane, is an oral retinoid (vitamin A derivative) used to treat severe or persistent acne. It works by dramatically reducing sebum production, normalising follicular keratinisation, and reducing the bacterial load in the skin.
For bodybuilders and steroid users, acne can be a frustrating side effect of androgenic compounds. Isotretinoin offers a near-permanent solution for many users – a single full course (typically 16 to 24 weeks at 0.5 to 1mg per kg body weight per day) can clear severe acne for years. Side effects include dry skin and lips (universal), dry eyes, joint pain, elevated liver enzymes, raised cholesterol, mood changes, and rare but serious effects like inflammatory bowel issues. Pregnancy must be strictly avoided due to extreme teratogenicity. Bloodwork during the course is essential. |
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| How is it used? | |
| Isotretinoin is taken once or twice daily with food (it is fat-soluble and absorption improves with a fatty meal). A standard course is 16 to 24 weeks, with the total cumulative dose calculated at around 120 to 150mg per kg of body weight.
For most users, this means 40 to 60mg per day for a 70 to 90kg adult. The dose can be adjusted up or down based on tolerance and skin response. Lower-dose protocols (20mg per day for 6 months) are also effective and produce fewer side effects. |
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| Dose | |
| This product is dosed at 20mg per tablet, 50 tablets per box. Typical dosing ranges from 20 to 60mg per day depending on body weight and acne severity. A common protocol is 20 to 40mg per day for 4 to 6 months, taken with a fatty meal for best absorption. |
| Advice From PhoenixFire: | |
| Take with a fatty meal | Isotretinoin is fat-soluble. Absorption can double when taken with a high-fat meal. |
| Moisturise constantly | Dry skin and lips are universal. Use a heavy moisturiser, lip balm, and eye drops throughout the course. |
| Bloodwork during the course | Check liver enzymes and lipid panel every 4 to 8 weeks during the course. Some users see significant cholesterol elevation. |
| Pregnancy is absolutely contraindicated | Female users must use reliable contraception throughout the course and for 1 month after. Birth defect risk is extreme. |
| Be patient | Many users see a worsening of acne in the first 2 to 4 weeks (‘purge’) before improvement begins. Stay the course. |
| FAQ: | |
| Q1 | How long until I see results from Accutane? |
| A1 | Initial improvement is usually visible by week 6 to 8. Significant clearing happens between weeks 12 and 16. Many users finish the course with completely clear skin. |
| Q2 | Will the acne come back after Accutane? |
| A2 | For most users, a full course produces long-lasting or permanent clearance. A minority require a second course years later. |
| Q3 | Can I work out hard on Accutane? |
| A3 | Yes, but joint pain and reduced healing capacity are common. Adjust training intensity if needed and stretch thoroughly. |
| Q4 | Do I need a low-dose or high-dose protocol? |
| A4 | Both work. Low-dose (20mg per day) for 6 months has fewer side effects. High-dose protocols clear acne faster but with more side effects. |
| Q5 | Are mood side effects real? |
| A5 | There is debate, but some users report mood changes or depression on Accutane. If you notice mood changes, talk to a doctor and consider lowering the dose or stopping. |
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